To investigate effect of water extract of Taraxaci Herba and Crataegi Fructus on human cancer cell-lines and immunocytes, this research estimated proliferation of A431 cell line, KHO-NP cell line, mouse thymocytes and mouse splenocytes, Nitric Oxide(NO) from macrophage, apoptosis and subpopulation of the mouse thymocytes.
The result were obtained as follows ;
1. Taraxaci Herba and Grataegi Fructus wasn´t effected the proliferation of A431 cell line.
2. Taraxaci Herba and Grataegi Fructus wasn´t effected the proliferation of KHOS-NP cell line.
3. Taraxaci Herba and Grataegi Fructus accelerated the proliferation of mouse thymocytes.
4. Taraxaci Herba and Grataegi Fructus inhibited the proliferation of mouse splenocytes.
5. Taraxaci Herba inhibited the production of NO from macrophages in vitro, being compared NPS+IFN treated group.
6. Grataegi Fructus accelerated the production of NO from macrophages in vitro, being compared NPS+IFN treated group.
7. Taraxaci Herba and Grataegi Fructus inhibited the production of NO from macrophages in vitro, being compared LPS+IFN treated group.
8. Taraxaci Herba and Grataegi Fructus accelerated the induction of apoptosis of the mouse thymocytes.
9. In subpopulation of mouse thymocytes, Taraxaci Herba decreased TH cell, but Crataegi Fructus increased TH cell.
10. In subpopulation of mose thymocytes, Taraxaci Herba decreased TC/TS cell.
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